I have just this minute cast off my Karisma/Scottish Tweed socks. I think they look fine in the two different yarns. (Edited 3.5.07 to add photo)
I am now going to do the unthinkable and NOT KNIT FOR A WEEK. Hopefully this will give my poor hands a rest as I am having problems with my thumb joint on my left hand. I think it is some kind of RSI. It does improve overnight so the rest should do it good. I am trying all kinds of things on it - glucosamine gel, ibuprofen gel, emu oil - all to no avail so a rest is definitely the answer. I hope I can last without getting withdrawal symptoms!!